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Our Research

Genomes carry genetic information. But genomes are not just abstract information: they are physically manifested as extremely long molecules that are intricately organized in the nucleus of every cell. The spatial organization of the genome is closely related to how it is accessed, regulated and activated by cellular machinery. We study this profound connection between genetic (and epigenetic) information and its physical organization.

Our research combines experimental and computational methods to gain a mechanistic understanding of how the genome encodes its organization and how this organization conveys biological function in various biological systems and diseases. Read more about our research here.

Lab News
  • Anna Golberg has joined us for her MSc/PhD – welcome Anna!
  • Lena Israitel has joined us for her PhD – welcome Lena!
  • Ari Feder is our new Research Scientist – welcome Ari!
  • Hagai Kariti has joined us for his MSc – welcome Hagai!
  • New review paper: “Chromosome Conformation Capture and Beyond: Toward an Integrative View of Chromosome Structure and Function” – read here.
  • Tal Feld has completed his MSc in Electrical Engineering – congratulations Tal!
  • Mor Guetta has joined us for her MSc/PhD – welcome Mor!
  • Our work has been featured in a Haaretz article about 3D genome organization!
  • New paper: “Attenuated chromatin compartmentalization in meiosis and its maturation in sperm development” – read here. On the cover of Nature Structural & Molecular Biology
NSMB cover

 

E-mail: noam.kaplan@technion.ac.il